- CASE FILE
I get into a state of paralysis when I take any anticholinergic.
ABOUT THIS CASE FILE
My symptoms started in high school with knee pain, I graduated in May 2017 and got accepted into a university in December 2017. While I was in college my knee pain started getting worse. In April 2018, my health started declining. My pain felt as if it moved to other joints in my body. Eventually, the pain was everywhere and it became suddenly hard to walk. I was taken into neurology and an EEG was done. They diagnosed me with Myoclonic Juvenile Epilepsy and I was put on a steady increase of Lamictal on June 2018. On July 1st, 2018, I become completely paralyzed and could not talk. I was taken to the ER, where they conducted a spinal tap. It came back positive for gram-negative cocci and was hospitalized. However, I was released on July 5th due to it being cross-contamination. I suffered greatly from the spinal tap and had to go in for an emergency blood patch. A few days after this, I suddenly was able to walk again. A month had passed and while being moved out, driving and going to college, I started to feel a similar pain in my knees that felt like it was spreading. After a week of feeling that, I lost all ability to walk and could no longer drive, go to college and had to move back in with my parents. July 18th I was given my first eval in physical therapy, and on September 5th, I was diagnosed with benign hypermobility syndrome. In October, my physical therapist realized that I was getting worse, I could no longer use any other aide but my wheelchair. On the 16th, I was taken to the ER because I could no longer control my legs. Within a few hours of being there, I became once again, completely paralyzed. I was taken to a bigger hospital where they performed multiple tests. The episodes would last 4-6 hours and my family and I noticed the symptoms were similar to sleep paralysis. I was released on October 19th with no cause found and was diagnosed with Conversion Disorder. Since my EEG was normal in the ER, I was instructed to come off Lamictal, after doing this, I become significantly better. On February 27th, 2019 I became paralyzed during a dentist appointment after being given laughing gas and was able to come out of the state, once it was removed. That's when my mother and I did research and found that both nitrous oxide and Lamictal are anticholinergic. Since then I have seen multiple specialists and they all have no answer to why I become paralyzed. They say its conversion disorder, even when I point out it only happens with a certain chemical. I do display other odd symptoms like waking up and not being able to talk, or becoming so fatigued that I cannot move very well, however, It is not a concern of mine because it is apart of Ehlers-Danlos symptoms. With the paralysis episodes, I have not met another person with EDS that displays these symptoms. It is considered an allergic reaction but unlike most, it's a very odd and rare reaction.