- CASE FILE
Severe muscle cramps for over a decade.
ABOUT THIS CASE FILE
Cramps started at 20. Worse at 30. Severe at 40. Disabling at 50. No "real" diagnosis. Pain management and medication helps. Muscle biopsies show type II fiber atrophy. No mitochondrial disorder. Blood work is normal (stellar actually). Not strong enough to work (Functional Capacity Evaluation). Physical exertion causes almost immediate cramping. Washing hair hurts my arms, etc. I'm in physical training, but it is difficult. Most recent exome testing revealed TRPA1 variant (ref. NYU 2018, possible treatment could be carbamazepine). I'm have been ready to give up many times. I reject Fibromyalgia based on symptoms. I reject post viral fatigue syndrome base on testing by infectious disease doctor. I reject Lyme Disease based on Igenex test results. I have many other lab results that rule out many other conditions, including Rheumatological and autoimmune disorders. I will entertain PTSD, but have already done treatment in this area. I still think the quick cramping is more physical than mental. I lean towards a rare disorder called Cramp Fasciculation syndrome. I hope you have seen this before and can help direct me to a treatment to get my life back.